Association of a Novel EEG Metric of Sleep Depth/Intensity with Attention-Deficit/Hyperactivity, Learning and Internalizing Disorders and their Pharmacotherapy in Adolescence.

Anna RicciSusan L CalhounFan HeJidong FangAlexandros N VgontzasDuanping LiaoEdward O BixlerMagdy YounesJulio Fernandez-Mendoza

Published in: Sleep (2021)

The greater ORP in unmedicated youth with ADHD/LD, and normalized levels in those on stimulants, suggests ORP is a useful metric of decreased NREM sleep depth/intensity in ADHD/LD. Antidepressants are associated with greater ORP/ORP-9, suggesting these medications induce cortical arousability.

Keyphrases

working memory
attention deficit hyperactivity disorder
physical activity
autism spectrum disorder
high intensity
optical coherence tomography
sleep quality
depressive symptoms
mental health
major depressive disorder
young adults
functional connectivity
resting state
bipolar disorder
high density