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Quercetin Pretreatment Attenuates Hepatic Ischemia Reperfusion-Induced Apoptosis and Autophagy by Inhibiting ERK/NF-κB Pathway.

Liwei WuQinghui ZhangWeiqi DaiSainan LiJiao FengJingjing LiTong LiuShizan XuWenwen WangXiya LuQiang YuKan ChenYujing XiaJie LuYingqun ZhouXiaoming FanChuanyong Guo
Published in: Gastroenterology research and practice (2017)
Apoptosis and autophagy caused by hepatic IR injury were inhibited by QE following a reduction in the release of inflammatory cytokines, and the relationship between the two may be associated with inactivation of the ERK/NF-κB pathway.
Keyphrases
  • signaling pathway
  • induced apoptosis
  • pi k akt
  • endoplasmic reticulum stress
  • cell cycle arrest
  • oxidative stress
  • cell death
  • toll like receptor
  • lps induced
  • inflammatory response