Alternative splicing in CEP290 mutant cats results in a milder phenotype than LCA CEP290 patients.
Andrea L MinellaKristina Narfström WiechelSimon M Petersen-JonesPublished in: Veterinary ophthalmology (2022)
The comparably milder phenotype of CEP290 mutant cats is likely due to the retained production of some full-length CEP290 protein with possible functional contributions from presence of truncated protein.