A Genetically Encoded Magnetic Resonance Imaging Reporter Enables Sensitive Detection and Tracking of Spontaneous Metastases in Deep Tissues.
Nivin N NyströmSean W McRaeFrancisco M MartinezJohn J KellyTimothy J SchollJohn A RonaldPublished in: Cancer research (2023)
An MRI reporter gene system optimized for tracking metastasis in deep tissues at high resolutions and able to detect spontaneous micrometastases in lungs of mice provides a useful tool for metastasis research.
Keyphrases
- sensitive detection
- magnetic resonance imaging
- contrast enhanced
- crispr cas
- gene expression
- quantum dots
- computed tomography
- diffusion weighted imaging
- genome wide
- loop mediated isothermal amplification
- copy number
- high fat diet induced
- metabolic syndrome
- genome wide identification
- insulin resistance
- skeletal muscle
- transcription factor