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Peritumoral administration of IFNβ upregulated mesenchymal stem cells inhibits tumor growth in an orthotopic, immunocompetent rat glioma model.

Jiaji MaoMinghui CaoFang ZhangJingzhong ZhangXiaohui DuanLiejing LuZehong YangXiang ZhangWangshu ZhuQinyuan ZhangZhe WangJun Shen
Published in: Journal for immunotherapy of cancer (2020)
MSCs can be used as cellular vehicles of IFNβ to treat malignant glioma effectively via peritumoral injection.
Keyphrases
  • mesenchymal stem cells
  • umbilical cord
  • dendritic cells
  • immune response
  • bone marrow
  • oxidative stress
  • cell therapy