Factors Predictive of Primary Resistance to Immune Checkpoint Inhibitors in Patients with Advanced Non-Small Cell Lung Cancer.
Soo-Chin LeeJoseph J ZhaoYu Yang SoonAdrian KeeSen Hee TayFolefac AminkengYvonne AngAlvin S C WongLavina D BharwaniBoon Cher GohRoss A SooPublished in: Cancers (2023)
Using SITC criteria, an elevated NLR (≥3) at 6 weeks, female gender and a later line of immunotherapy treatment (≥2 lines) were predictive factors of developing primary resistance to ICI monotherapy in patients with advanced NSCLC.