Hoxb5 reprogrammes murine multipotent blood progenitors into haematopoietic stem cell-like cells.

Dehao HuangQianhao ZhaoMengyun ZhangQitong WengQi ZhangKaitao WangFang DongHui ChengFangxiao HuJinyong Wang

Published in: Cell proliferation (2022)

Our current study uncovers that Hoxb5 can empower MPP with self-renewal ability and indicates an alternative approach for generating HSC-like cells in vivo from blood lineage cells.

Keyphrases

stem cells
induced apoptosis
cell cycle arrest
single cell
signaling pathway
oxidative stress
cell proliferation
pi k akt