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Metabolic profiling of smoking, associations with type 2 diabetes and interaction with genetic susceptibility.

Yuxia WeiSara HäggJonathan K L MakTiinamaija TuomiYiqiang ZhanSofia Carlsson
Published in: European journal of epidemiology (2024)
The increased risk of T2D in smokers may be mediated through effects on the metabolome, and the influence of such metabolic alterations on diabetes risk may be amplified in individuals with genetic susceptibility to T2D or insulin resistance.
Keyphrases
  • insulin resistance
  • type diabetes
  • smoking cessation
  • genome wide
  • cardiovascular disease
  • copy number
  • glycemic control
  • adipose tissue
  • high fat diet
  • polycystic ovary syndrome
  • dna methylation