The Impact of Gastroesophageal Reflux Disease and Proton Pump Inhibitor Use on the Risk of Repeat Catheter Ablation for Atrial Fibrillation.
Jennifer X CaiMiguel AlgaraWai-Kit LoSunil KapurWalter Wai-Yip ChanPublished in: Clinical and translational gastroenterology (2024)
GERD was an independent predictor for risk of repeat AF ablation within one year, even after controlling for major cardiovascular comorbidities and confounders. PPI therapy modulated this risk, as repeat ablation-free survival for PPI-treated GERD was non-inferior to reflux-free patients.
Keyphrases
- catheter ablation
- atrial fibrillation
- gastroesophageal reflux disease
- left atrial
- left atrial appendage
- free survival
- end stage renal disease
- oral anticoagulants
- newly diagnosed
- direct oral anticoagulants
- ejection fraction
- heart failure
- chronic kidney disease
- peritoneal dialysis
- protein protein
- prognostic factors
- coronary artery disease
- percutaneous coronary intervention
- stem cells
- small molecule
- patient reported
- left ventricular
- acute coronary syndrome