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The temporal association of CapZ with early endosomes regulates endosomal trafficking and viral entry into host cells.
Huazhang Zhu
Dawei Wang
Zuodong Ye
Lihong Huang
Wenjie Wei
Kui Ming Chan
Rongxin Zhang
Liang Zhang
Jianbo Yue
Published in:
BMC biology (2024)
These results indicate that the temporal association of CapZ with EEs facilitates early-to-late endosome transition (physiologically) and the release of the viral genome from endocytic vesicles (pathologically).
Keyphrases
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sars cov
induced apoptosis
gene expression
cell death