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Astrocytic insulin-like growth factor-1 prevents excitotoxic downregulation of adenosine deaminase acting on RNA in calcium dynamics.

Wei ChenBin HeZheng Ping
Published in: Journal of cellular biochemistry (2018)
Astrocytic IGF-1 has a neuroprotective role in preventing excitotoxic downregulation of ADAR1 in mediating calcium dynamics via STAT2.
Keyphrases
  • cell proliferation
  • signaling pathway
  • growth hormone
  • pi k akt
  • mouse model
  • binding protein
  • protein kinase