Human renal response to furosemide: Simultaneous oxygenation and perfusion measurements in cortex and medulla.

Bryan Thomas HaddockHenrik B W LarssonSusan FrancisUlrik B Andersen

Published in: Acta physiologica (Oxford, England) (2019)

Furosemide induced the anticipated increase in renal medullary oxygenation, attributable exclusively to a decrease in renal oxygen consumption, since no change of RAF, cortical or medullary perfusion could be demonstrated. All measures and the induced changes were reproducible.

Keyphrases

high glucose
endothelial cells
diabetic rats
drug induced
magnetic resonance imaging
blood flow
oxidative stress
computed tomography
induced pluripotent stem cells