The Relationship Between Lipoproteins and Insulin Sensitivity in Youth With Obesity and Abnormal Glucose Tolerance.
Stephanie T ChungLorraine E Levitt KatzNicolas Stettler-DavisJustine ShultsArthur ShermanJoon HaDarko StefanovskiRay C BostonDaniel James RaderSheela N MaggePublished in: The Journal of clinical endocrinology and metabolism (2022)
Among youth with obesity, insulin resistance was associated with an atherogenic lipoprotein/lipid profile and cIMT, regardless of glucose tolerance status. Insulin resistance in AGT youth was associated with a shift to smaller HDL-P compared to normoglycemic youth with obesity. Alterations in HDL-P metabolism may be early adverse manifestations of hyperglycemia in youth with obesity.