Theoretical characterisation of strand cross-correlation in ChIP-seq.

Hayato AnzawaHitoshi YamagataKengo Kinoshita

Published in: BMC bioinformatics (2020)

We present the first theoretical insights into the strand cross-correlation, and the results reveal the potential and the limitations of strand cross-correlation analysis. Our quality assessment framework using VSN provides peak call-independent QC and will help in the evaluation of peak call analysis in ChIP-seq experiments.

Keyphrases

genome wide
single cell
high throughput
rna seq
circulating tumor cells
dna methylation
risk assessment
data analysis