Tandem Wittig Reaction-Ring Contraction of Cyclobutanes: A Route to Functionalized Cyclopropanecarbaldehydes.

Federico CuccuLorenzo SerusiAlberto Luridiana Francesco Secci Pierluigi Caboni David J Aitken Angelo Frongia

Published in: Organic letters (2019)

An original tandem reaction consisting of a Wittig reaction-ring contraction process between α-hydroxycyclobutanone and phosphonium ylides has been developed. Highly functionalized cyclopropanecarbaldehydes are obtained in good to high yield.

Keyphrases

quantum dots
smooth muscle
ionic liquid
electron transfer
mass spectrometry
simultaneous determination