Ultrashort echo time magnetic resonance imaging of the osteochondral junction.
Alecio F LombardiMonica GumaChristine B ChungEric Y ChangJiang DuYa-Jun MaPublished in: NMR in biomedicine (2022)
Osteoarthritis is a common chronic degenerative disease that causes pain and disability with increasing incidence worldwide. The osteochondral junction is a dynamic region of the joint that is associated with the early development and progression of osteoarthritis. Despite the substantial advances achieved in the imaging of cartilage and application to osteoarthritis in recent years, the osteochondral junction has received limited attention. This is primarily related to technical limitations encountered with conventional MR sequences that are relatively insensitive to short T2 tissues and the rapid signal decay that characterizes these tissues. MR sequences with ultrashort echo time (UTE) are of great interest because they can provide images of high resolution and contrast in this region. Here, we briefly review the anatomy and function of cartilage, focusing on the osteochondral junction. We also review basic concepts and recent applications of UTE MR sequences focusing on the osteochondral junction.
Keyphrases
- contrast enhanced
- magnetic resonance
- magnetic resonance imaging
- high resolution
- platelet rich plasma
- diffusion weighted
- rheumatoid arthritis
- computed tomography
- knee osteoarthritis
- gene expression
- diffusion weighted imaging
- multiple sclerosis
- chronic pain
- risk factors
- extracellular matrix
- neuropathic pain
- pain management
- optical coherence tomography
- convolutional neural network
- high speed
- fluorescence imaging