Post-acute sequelae of SARS-CoV-2 infection: relationship of central nervous system manifestations with physical disability and systemic inflammation.
Geraldo Filho BusattoAdriana Ladeira de AraújoJoão Mauricio Castaldelli-MaiaRodolfo Furlan DamianoMarta ImamuraBruno F GuedesFabio de Rezende PinnaMarcio Valente Yamada SawamuraMárcio C ManciniKatia R da SilvaMichelle L GarciaNairo SumitaAndre Russowsky BrunoniAlberto J da Silva DuarteEmmanuel A BurdmannEsper G KallasGiovanni G CerriRicardo NitriniRicardo F BentoVanderson Geraldo RochaHeraldo Possolo de SouzaEuripedes C MiguelCarlos R R de CarvalhoOrestes V ForlenzaLinamara Rizzo Batistellanull nullPublished in: Psychological medicine (2022)
Different symptoms that persist for several months after moderate or severe COVID-19 may unite within one latent trait of PASC. This trait is dominated by fatigue and psychiatric symptoms, and is associated with objective signs of physical disability and persistent systemic inflammation.
Keyphrases
- mental health
- sleep quality
- physical activity
- multiple sclerosis
- coronavirus disease
- genome wide
- sars cov
- liver failure
- drug induced
- respiratory syndrome coronavirus
- respiratory failure
- early onset
- cerebrospinal fluid
- aortic dissection
- dna methylation
- depressive symptoms
- gene expression
- hepatitis b virus
- extracorporeal membrane oxygenation
- acute respiratory distress syndrome