Asymptomatic Pyuria as a Prognostic Biomarker in Autosomal Dominant Polycystic Kidney Disease.

Brian E Jones Yaman G MkhaimerLaureano J RangelMaroun ChedidPhillip J Schulte Alaa K MohamedReem M NealDalia ZubidatAmarjyot K RandhawaChristian HannaAdriana V GregoryTimothy L Kline Ziad M Zoghby Sarah R SenumPeter C HarrisVicente E TorresFouad T Chebib

Published in: Kidney360 (2021)

AP is associated with kidney failure and faster kidney function decline irrespective of the ADPKD gene, cystic burden, and cystic growth. These results support AP as an enriching prognostic biomarker for the rate of disease progression.

Keyphrases

polycystic kidney disease
transcription factor
genome wide
copy number
risk factors
gene expression
genome wide identification