Urine concentrating defect as presenting sign of progressive renal failure in Bardet-Biedl syndrome patients.

Miriam ZacchiaFrancesca Del Vecchio BlancoAnnalaura TorellaRaffaele RaucciGiancarlo BlasioMaria Elena OnoreEmanuela MarcheseFrancesco TrepiccioneCaterina VitaglianoValentina Di IorioPerna AlessandraFrancesca SimonelliVincenzo NigroGiovambattista Capasso Davide Viggiano

Published in: Clinical kidney journal (2020)

Hyposthenuria is a warning sign predicting poor renal outcome in BBS. The pathophysiology of this defect is most likely beyond defective tubular function.

Keyphrases

end stage renal disease
ejection fraction
newly diagnosed
chronic kidney disease
multiple sclerosis
case report
peritoneal dialysis
prognostic factors
patient reported outcomes
endothelial cells
high glucose