microRNA-mRNA Networks Linked to Inflammation and Immune System Regulation in Inflammatory Bowel Disease.

Carina de F de SíbiaAna E V QuaglioEllen C S de OliveiraJéssica Nunes PereiraJovita R AriedeRainer M L LapaFábio E SeverinoPatrícia Pintor Reis Ligia Yukie SassakiRogerio Saad-Hossne

Published in: Biomedicines (2024)

The identified miRNAs play roles in regulating genes associated with immune system regulation and inflammation in IBD. Such miRNAs and their target genes have the potential to serve as clinically relevant biomarkers. These findings hold promise for enhancing the accuracy of diagnoses and facilitating the development of personalized treatment strategies for individuals with various forms of IBD.

Keyphrases

oxidative stress
ulcerative colitis
big data
gene expression
climate change
dna methylation
transcription factor