Influence of citrate concentration on the activation of blood cells in an in vitro dialysis setup.

Jakob GubensekKarin StroblStephan HarmRene WeissTanja EichhornJadranka Buturovic-PonikvarViktoria WeberJens Hartmann

Published in: PloS one (2018)

Our data indicate that an increase in the citrate concentration from 3 mM to 4 mM further dampens cellular activation, thereby improving biocompatibility. A concentration of 4 mM citrate might therefore be optimal for use in clinical practice.

Keyphrases

clinical practice
induced apoptosis
chronic kidney disease
cell cycle arrest
electronic health record
big data
machine learning
cell death
cell proliferation