Genotype-Phenotype Correlations and Clinical Outcomes in 155 Cases of Pheochromocytoma and Paraganglioma.

Hogan WangAlexander J PapachristosAnthony J GillRoderick Clifton-BlighAhmad M AnissAnthony GloverMark SywakStan B Sidhu

Published in: World journal of surgery (2022)

Genotypic characteristics strongly influence disease presentation and recurrence risk, which may occur more than 5 years after initial treatment. Routine genetic testing of PPGL patients is warranted given the high prevalence of mutations, allowing for prognostication and tailored follow-up. In the presence of germline mutations, follow-up should be life-long.

Keyphrases

end stage renal disease
ejection fraction
newly diagnosed
prognostic factors
peritoneal dialysis
clinical practice
case report
dna damage
oxidative stress