Clinicopathological characteristics of non-B non-C hepatocellular carcinoma without past hepatitis B virus infection.

Takefumi KimuraAkira KobayashiNaoki TanakaKenji SanoMichiharu KomatsuNaoyuki FujimoriTomoo YamazakiSoichiro ShibataYuki IchikawaSatoru JoshitaTakeji UmemuraAkihiro MatsumotoAkira HoriuchiHiromitsu MoriShuichi WadaKendo KiyosawaShin-Ichi MiyagawaEiji Tanaka

Published in: Hepatology research : the official journal of the Japan Society of Hepatology (2016)

Liver fibrosis and steatosis are risk factors of HCC regardless of past HBV infection and ethanol consumption. The present results also indicate the possibility of hepatocarcinogenesis independent of hepatic steatosis, inflammation and fibrosis, ethanol intake, and past HBV infection.

Keyphrases

liver fibrosis
hepatitis b virus
risk factors
liver failure
oxidative stress
insulin resistance
high fat diet
metabolic syndrome
physical activity
weight gain