Quantitative analysis of 11-dehydrocorticosterone and corticosterone for preclinical studies by liquid chromatography/triple quadrupole mass spectrometry.

Manu VermaKaren SooyGeorge JustMark NixonRuth MorganRuth AndrewKaren E ChapmanNatalie Z M Homer

Published in: Rapid communications in mass spectrometry : RCM (2020)

This LC/MS method is suitable for the reliable analysis of 11-DHC and CORT following simple LLE of murine plasma, bringing preclinical analysis in line with recommendations for clinical endocrinology and biochemistry.

Keyphrases

liquid chromatography
mass spectrometry
high resolution mass spectrometry
tandem mass spectrometry
high performance liquid chromatography
gas chromatography
simultaneous determination
cell therapy
capillary electrophoresis
solid phase extraction
high resolution
clinical practice
bone marrow
case control
ms ms