Pharmacological antagonism of receptor for advanced glycation end products signaling promotes thermogenesis, healthful body mass and composition, and metabolism in mice.

Robin A WilsonLakshmi ArivazhaganHenry H RuizBoyan ZhouKun QianMichaele B ManigrassoRollanda BernadinKaamashri MangarAlexander ShekhtmanHuilin LiRavichandran Ramasamy Ann Marie Schmidt

Published in: Obesity (Silver Spring, Md.) (2023)

Pharmacological antagonism of RAGE signaling is a potent strategy to optimize healthful body mass and composition and metabolic fitness.

Keyphrases

adipose tissue
physical activity
body composition
type diabetes
insulin resistance
high fat diet induced