Combining urine antigen and blood polymerase chain reaction for the diagnosis of disseminated histoplasmosis in hospitalized patients with advanced HIV disease.

José Ernesto VidalPaula Custodio WerlangBruno M MunizCaroline Martins RegoRenata Elisie BarbalhoAndré Miranda BaptistaJoao Paulo TellesAllecineia Bispo da CruzIngrid de Siqueira PereiraRicardo GavaRosa MarcussoAlessandro C PasqualottoVera Lucia Pereira-Chioccola

Published in: Medical mycology (2021)

In this prospective cohort study carried-out in a referral center in São Paulo, Brazil, we found a high frequency of AIDS-related disseminated histoplasmosis (8/106, 7.5%). We used urine antigen test and blood PCR assay to improve the diagnosis of this opportunistic disease.

Keyphrases

high frequency
antiretroviral therapy
transcranial magnetic stimulation
hiv infected
human immunodeficiency virus
hiv positive
primary care
hepatitis c virus
high throughput
hiv testing
men who have sex with men
south africa