Genomics and transcriptomics yields a system-level view of the biology of the pathogen Naegleria fowleri.
Emily K HermanAlex GreningerMark van der GiezenMichael L GingerInmaculada Ramirez-MaciasHaylea C MillerMatthew J MorganAnastasios D TsaousisKatrina VelleRomana VargováKristína ZáhonováSebastian Rodrigo NajleGeorgina MacIntyreNorbert MullerMattias WittwerDenise C Zysset-BurriMarek EliášClaudio H SlamovitsMatthew T WeirauchLillian Fritz-LaylinFrancine Marciano-CabralGeoffrey J PuzonTom WalshCharles ChiuJoel Bryan DacksPublished in: BMC biology (2021)
In-depth analysis of Naegleria genomes and transcriptomes provides a model of cellular systems involved in opportunistic pathogenicity, uncovering new angles to understanding the biology of a rare but highly fatal pathogen.