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Measuring Tumor Metabolism in Pediatric Diffuse Intrinsic Pontine Glioma Using Hyperpolarized Carbon-13 MR Metabolic Imaging.

Adam W AutryRintaro HashizumeC David JamesPeder E Z LarsonDaniel B VigneronIlwoo Park
Published in: Contrast media & molecular imaging (2018)
Results from this study characterized pyruvate and lactate metabolism in orthotopic DIPG xenografts and suggest that hyperpolarized 13C MRSI may serve as a noninvasive imaging technique for in vivo monitoring of biochemical processes in patients with DIPG.
Keyphrases
  • high resolution
  • magnetic resonance
  • magnetic resonance imaging
  • computed tomography
  • photodynamic therapy
  • fluorescence imaging
  • high grade
  • childhood cancer