Scolopendra subspinipes mutilans Extract Suppresses Inflammatory and Neuropathic Pain In Vitro and In Vivo.

Lakkyong HwangIl-Gyu KoJun-Jang JinSang-Hoon KimChang-Ju KimJung Won JeonJin-Hee Han

Published in: Evidence-based complementary and alternative medicine : eCAM (2018)

Our results suggest that SSM suppresses the production of inflammatory factors via the NF-κB pathway and accelerates the morphological and functional recovery of the peripheral nervous system. Hence, SSM may be a useful therapeutic candidate for treatment of neuropathic pain diseases.

Keyphrases

neuropathic pain
signaling pathway
oxidative stress
spinal cord
spinal cord injury
pi k akt
lps induced
immune response
nuclear factor
cell proliferation
anti inflammatory