SARS-CoV-2 neutralization and serology testing of COVID-19 convalescent plasma from donors with nonsevere disease.
Thomas J GniadekJoshua M ThiedeWilliam E MatchettAbigail R GressKathryn A PapeJessica K FiegeMarc K JenkinsVineet D MenacheryRyan A LangloisTyler D BoldPublished in: Transfusion (2020)
The strength of the relationship between antigen-binding activity and neutralization varies depending on the clinical assay used. Units in the highest tertile of binding activity for each assay are predominantly comprised of those with the greatest neutralization activity.