PSC is rarely seen in clinical practice and commonly occurs in elder men with smoking history. Tumor tissue PD-L1 expression ≥1% and MET abnormalities may predict inferior prognosis of PSC and lymph node metastasis was determined as the independent prognosticator of PSC. Surgical resection along with adjuvant medical treatment is the cornerstone for early and locally advanced patients, and the clinical utility of molecular targeting therapy and immunotherapy in PSC needs to be further investigated.
Keyphrases
- lymph node metastasis
- squamous cell carcinoma
- end stage renal disease
- locally advanced
- clinical practice
- ejection fraction
- chronic kidney disease
- pulmonary hypertension
- early stage
- peritoneal dialysis
- papillary thyroid
- rectal cancer
- neoadjuvant chemotherapy
- mesenchymal stem cells
- smoking cessation
- drug delivery
- high resolution
- lymph node
- combination therapy
- patient reported