Complete vertebrate mitogenomes reveal widespread repeats and gene duplications.

Giulio FormentiArang RhieJennifer BalaccoBettina HaaseJacquelyn MountcastleOlivier FedrigoSamara BrownMarco Rosario CapodiferroFarooq O Al-AjliRoberto AmbrosiniPeter HoudeSergey KorenKaren OliverMichelle SmithJason SkeltonEmma BetteridgeJale DolucanCraig CortonIliana BistaJames TorranceAlan TraceyJonathan WoodMarcela Uliano-SilvaKerstin HoweShane McCarthySylke WinklerWoori KwakJonas KorlachArkarachai FungtammasanDaniel FordhamVania CostaSimon MayesMatteo ChiaraDavid S HornerEugene MyersRichard DurbinAlessandro AchilliEdward L BraunAdam M PhillippyErich D Jarvisnull null

Published in: Genome biology (2021)

Our results indicate that even in the "simple" case of vertebrate mitogenomes the completeness of many currently available reference sequences can be further improved, and caution should be exercised before claiming the complete assembly of a mitogenome, particularly from short reads alone.

Keyphrases

genome wide
copy number
single cell
dna methylation
transcription factor
genetic diversity