Density and tailored breast cancer screening: practice and prediction - an overview.
Georg J WengertThomas H HelbichPanagiotis KapetasPascal At BaltzerKatja PinkerPublished in: Acta radiologica open (2018)
Mammography, as the primary screening modality, has facilitated a substantial decrease in breast cancer-related mortality in the general population. However, the sensitivity of mammography for breast cancer detection is decreased in women with higher breast densities, which is an independent risk factor for breast cancer. With increasing public awareness of the implications of a high breast density, there is an increasing demand for supplemental screening in these patients. Yet, improvements in breast cancer detection with supplemental screening methods come at the expense of increased false-positives, recall rates, patient anxiety, and costs. Therefore, breast cancer screening practice must change from a general one-size-fits-all approach to a more personalized, risk-based one that is tailored to the individual woman's risk, personal beliefs, and preferences, while accounting for cost, potential harm, and benefits. This overview will provide an overview of the available breast density assessment modalities, the current breast density screening recommendations for women at average risk of breast cancer, and supplemental methods for breast cancer screening. In addition, we will provide a look at the possibilities for a risk-adapted breast cancer screening.
Keyphrases
- healthcare
- breast cancer risk
- primary care
- end stage renal disease
- newly diagnosed
- chronic kidney disease
- cardiovascular disease
- pregnant women
- coronary artery disease
- skeletal muscle
- ejection fraction
- peritoneal dialysis
- insulin resistance
- young adults
- cardiovascular events
- contrast enhanced
- real time pcr
- quantum dots
- pregnancy outcomes
- childhood cancer
- dual energy