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Network-driven analysis of human-Plasmodium falciparum interactome: processes for malaria drug discovery and extracting in silico targets.

Francis E AgamahDelesa DamenaMichelle SkeltonAnita GhansahGaston K MazanduEmile R Chimusa
Published in: Malaria journal (2021)
Host-pathogen network analysis reveals potential drug targets and biological processes and pathways subverted by P. falciparum to enhance its within malaria host survival. The results presented have implications for drug discovery and will inform experimental studies.
Keyphrases
  • drug discovery
  • plasmodium falciparum
  • endothelial cells
  • molecular docking
  • drug induced
  • case control
  • free survival
  • network analysis
  • risk assessment