Late-onset neuromyelitis optica spectrum disorder: The importance of autoantibody serostatus.

Maria Sepúlveda Guillermo Delgado-GarcíaYolanda BlancoNuria Sola-VallsElena H Martinez-LapiscinaThaís ArmanguéCarmen MontejoIrene Pulido-ValdeolivasEugenia Martinez-HernandezHelena AriñoDomingo EscuderoRaquel Ruiz-GarcíaSara LlufriuJosep DalmauFrancesc GrausAlbert Saiz

Published in: Neurology(R) neuroimmunology & neuroinflammation (2019)

Patients with LO-NMOSD have similar clinical presentation but worse outcome than EO-NMOSD when they are double seronegative or AQP4-IgG positive. Serostatus and residual disability after first attack are the main predictors of LO-NMOSD outcome.

Keyphrases

late onset
spectrum disorder
early onset