Neuroimaging correlates of persistent fatigue in older adults: A secondary analysis from the Multidomain Alzheimer Preventive Trial (MAPT) trial.

Davide AngioniBeatrice ArosioJeremy RaffinKelly Virecoulon GiudiciJean François ManginAli BouyahiaMarie ChupinClara FischerEmmanuelle GourieuxYves RollandSandra De BreuckerBruno VellasPhilipe de Souto Barretonull null

Published in: Aging & mental health (2021)

Persistent fatigue was cross-sectionnally associated with higher white matter hyperintensity volume in older adults. Further longitudinal studies, using an assessment tool specifically designed and validated for measuring fatigue, are needed to confirm our findings.

Keyphrases

white matter
sleep quality
phase iii
physical activity
study protocol
phase ii
clinical trial
open label
depressive symptoms