Real-world evidence on siponimod treatment in patients with secondary progressive multiple sclerosis.
Liesa Regner-NelkeMarc PawlitzkiAlice WillisonLeoni RolfesSinem-Hilal OezalpChristopher NelkeTristan KölscheMelanie KorsenMatthias GrotheSergiu GroppaFelix LuessiSinah EngelGereon NellesEckhard BonmannHolger RoickAnke FriedrichPhilipp KnornHarald LandefeldZoltan BiroMichael ErnstAntonios BayasMartina MenacherKatja AkgünChristoph KleinschnitzTobias RuckTjalf ZiemssenRefik PulSven Guenther MeuthPublished in: Neurological research and practice (2022)
Treatment with siponimod had an overall stabilizing effect regarding clinical and radiological outcome measures. However, there is a need for more intensive treatment management and monitoring to identify disease progression and AE.