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In silico repurposing of antipsychotic drugs for Alzheimer's disease.

Shivani KumarSuman ChowdhurySuresh Kumar
Published in: BMC neuroscience (2017)
The present study have led to unravel the potential of leading antipsychotic drugs such as pimozide, bromperidol, melperone, anisoperidone, benperidol and anisopirol against multiple targets associated with AD. Benperidol was found to be the best candidate drug interacting with different target proteins involved in AD.
Keyphrases
  • drug induced
  • cognitive decline
  • molecular docking
  • protein kinase
  • human health
  • climate change