Testosterone supplementation and bone parameters: a systematic review and meta-analysis study.

G CoronaW VenaA PizzocaroV A GiagulliD FrancomanoG RastrelliG MazziottiA AversaA M IsidoriR PivonelloL VignozziE MannucciMario MaggiA Ferlin

Published in: Journal of endocrinological investigation (2022)

TRT is able to inhibit bone resorption and increase bone mass, particularly at the lumbar spine level and when the duration is long enough to allow the anabolic effect of T and estrogens on bone metabolism to take place.

Keyphrases

bone mineral density
bone loss
soft tissue
bone regeneration
postmenopausal women
body composition
replacement therapy