Quantifying the rate of recurrence of postoperative Crohn's disease with biological therapy. A meta-analysis.
Sneha R JainZachariah G W OwYip-Han ChinWen H LimGwyneth KongHui Y ThamNeng W WongChoon S ChongFung J FooWebber Pak Wo ChanPublished in: Journal of digestive diseases (2021)
Anti-TNF-α agents are effective at preventing clinical, endoscopic and surgical POR of CD. The timing of initiating biological therapy after surgery has no significant effect on the rate of POR. The efficacy of infliximab and adalimumab for postoperative recurrence prevention is similar.