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Beta3-Adrenergic Receptor Activation Alleviates Cardiac Dysfunction in Cardiac Hypertrophy by Regulating Oxidative Stress.

Mingming ZhangYuerong XuJianghong ChenChaoshi QinJing LiuDong GuoRui WangJianqiang HuQing ZouJingxiao YangZikuan WangXiaolin Niu
Published in: Oxidative medicine and cellular longevity (2021)
β3-AR stimulation alleviated cardiac dysfunction and reduced cardiomyocytes apoptosis, oxidative stress, and fibrosis by inhibiting NADPH oxidases. In addition, the protective effect of β3-AR is largely attributed to nNOS activation in cardiac hypertrophy.
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