Drug susceptibility patterns of Mycobacterium tuberculosis from adults with multidrug-resistant tuberculosis and implications for a household contact preventive therapy trial.
Anne-Marie DemersSoyeon KimSara McCallumKathleen EisenachMichael HughesLinda NainiAlberto Mendoza-TiconaNeeta PradhanKim NarunskySelvamuthu PoongulaliSharlaa Badal-FaesenCaryn UptonElizabeth SmithN Sarita ShahGavin ChurchyardAmita GuptaAnneke HesselingSusan Swindellsnull nullPublished in: BMC infectious diseases (2021)
RR-TB was detected in all routine specimens but only 75% had documented MDR-TB, illustrating the need for expanded DST beyond Xpert MTB/RIF to target preventive therapy for HHC.
Keyphrases
- mycobacterium tuberculosis
- multidrug resistant
- pulmonary tuberculosis
- drug resistant
- acinetobacter baumannii
- gram negative
- klebsiella pneumoniae
- study protocol
- phase iii
- clinical trial
- clinical practice
- phase ii
- emergency department
- bone marrow
- escherichia coli
- drug induced
- cell therapy
- hiv infected
- replacement therapy