Deletion of RasGRF1 Attenuated Interstitial Fibrosis in Streptozotocin-Induced Diabetic Cardiomyopathy in Mice through Affecting Inflammation and Oxidative Stress.

Tzu-Hsien TsaiCheng-Jei LinSarah ChuaSheng-Ying ChungShyh-Ming ChenChien-Ho LeeChi-Ling Hang

Published in: International journal of molecular sciences (2018)

The deletion of RasGRF1 attenuated myocardial fibrosis and improved cardiac function in diabetic mice through inhibiting inflammation and oxidative stress.

Keyphrases

oxidative stress
diabetic rats
ischemia reperfusion injury
dna damage
induced apoptosis
type diabetes
heart failure
signaling pathway
left ventricular
high fat diet
liver fibrosis
heat shock
wound healing
drug induced
wild type