Sex-Specific Effects of Blood Pressure Lowering Pharmacotherapy for the Prevention of Cardiovascular Disease: An Individual Participant-Level Data Meta-Analysis.

Zeinab Bidel Milad Nazarzadeh Dexter Canoy Emma Copland Eva Gerdts Mark Woodward Ajay K Gupta Christopher M Reid William C Cushman Kristian WachtellKoon TeoBarry R Davis John Chalmers Carl J Pepine Kazem Rahiminull null

Published in: Hypertension (Dallas, Tex. : 1979) (2023)

The effects of BP reduction were similar in women and men across all BP and age categories at randomization and with no evidence to suggest that drug classes had differing effects by sex. This study does not substantiate sex-based differences in BP-lowering treatment.

Keyphrases

cardiovascular disease
blood pressure
systematic review
polycystic ovary syndrome
meta analyses
type diabetes
big data
emergency department
cardiovascular risk factors
metabolic syndrome
adipose tissue
skeletal muscle
drug induced
weight loss