Esophageal pH increments associated with post-reflux swallow-induced peristaltic waves show the occurrence and relevance of esophago-salivary reflex in clinical setting.
Marzio FrazzoniLeonardo FrazzoniMentore RibolsiNicola de BortoliSalvatore ToloneRita ConigliaroElena ArsièRoberto PenaginiMichele CicalaEdoardo SavarinoPublished in: Neurogastroenterology and motility : the official journal of the European Gastrointestinal Motility Society (2021)
Considerable PSPW-associated pH increments demonstrate the occurrence of esophago-salivary reflex in clinical setting. Lower increments in PPI-refractory RRH cases show the clinical relevance of esophago-salivary reflex, confirming that PSPW represents a defense mechanism against reflux. PSPW-associated ∆pH can efficiently predict PPI response in patients undergoing off-therapy impedance-pH monitoring.