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Urine Galectin-3 binding protein reflects nephritis activity in systemic lupus erythematosus.

Francesca FaustiniHelena IdborgEnrico FuzziAnders LarssonWen-Rong LieSven PötzschShinji L OkitsuElisabet SvenungssonIva Gunnarsson
Published in: Lupus (2022)
Given its ability to discriminate LN patients from active non-renal and inactive SLE patients, the observed correlation with the activity index in renal biopsies, and its levels declining following treatment, u-Gal-3BP shows promise as a non-invasive urinary biomarker to help detecting and to monitor renal involvement in SLE patients and should be validated in larger cohorts.
Keyphrases
  • ejection fraction
  • newly diagnosed
  • systemic lupus erythematosus
  • prognostic factors
  • patient reported outcomes
  • disease activity
  • combination therapy