The potential impact of coagulation factor XIII in trauma-induced coagulopathy - a retrospective case series analysis.
Michaela WilhelmiAlexander AlbrechtChristian MackeMathias WilhelmiMohammed OmarMarcel WinkelmannJan-Dierk ClausenPublished in: European journal of trauma and emergency surgery : official publication of the European Trauma Society (2023)
The substitution of FXIII in patients who were more seriously compromised due to higher lactate levels and who presented with initially more severe bleedings than patients in the control group, resulted in a comparable transfusion necessity after 24 h. Thus, we guess that the substitution of FXIII in severely injured patients with ongoing bleeding might have an impact on their clinical outcome.