Pentamidine inhibits prostate cancer progression via selectively inducing mitochondrial DNA depletion and dysfunction.

Lin LiuFan WangYu TongLin-Feng LiYanfeng LiuWei-Qiang Gao

Published in: Cell proliferation (2019)

Pentamidine can efficiently suppress prostate cancer progression and may serve as a novel mitochondria-targeted therapeutic agent for prostate cancer.

Keyphrases

prostate cancer
mitochondrial dna
radical prostatectomy
copy number
cell death
oxidative stress
cancer therapy
drug delivery
endoplasmic reticulum