Iodine-mediated electrochemical C(sp 3 )-H cyclization: the synthesis of quinazolinone-fused N-heterocycles.

An efficient iodine-mediated electrochemical C(sp 3 )-H cyclization was developed under mild conditions. A variety of functionalized quinazolinone-fused N-heterocycles can be obtained with good to excellent yields by virtue of this method. The reaction features a broad substrate scope and scalability, and is metal-free and chemical oxidant-free.