Exploring Definitions and Predictors of Severe Asthma Clinical Remission Post-Biologic in Adults.
Luis Perez-de-LlanoGhislaine SceloTrung N TranTham T LeMalin FageråsBorja García CosioMatthew PetersPaul E PfefferMona Al-AhmadRiyad O Al-LehebiAlan AltrajaCeline BergeronLeif H BjermerAnne S BjerrumLakmini BulathsinhalaJohn BusbyDiana J Cano RosalesGiorgio W CanonicaVictoria A CarterJeremy CharriotGeorge C ChristoffEve J DentonDelbert R DorscheidMaria J Fernandez SanchezJoão A FonsecaPeter G GibsonCeline Y Y GohLiam G HeaneyEnrico HefflerMark HewTakashi IwanagaRohit KatialMariko S KohPiotr KunaDésirée E S Larenas-LinnemannLauri LehtimäkiBassam MahboubNeil MartinHisako MatsumotoAndrew N Menzies-GowNikolaos G PapadopoulosTodor A PopovCeleste M PorsbjergPujan PatelChin Kook RheeMohsen SadatsafaviCamille TailléCarlos Arturo Torres-DuqueMing-Ju TsaiCharlotte S UlrikJohn W UphamAnna von BülowEileen WangMichael E WechslerDavid J PricePublished in: American journal of respiratory and critical care medicine (2024)
One in 5 patients achieved 4-domain remission within 1-year of biologic-initiation. Patients with less severe impairment and shorter asthma duration at initiation had a greater chance of achieving remission post-biologic, indicating that biologic treatment should not be delayed if remission is the goal. This article is open access and distributed under the terms of the Creative Commons Attribution Non-Commercial No Derivatives License 4.0 (http://creativecommons.org/licenses/by-nc-nd/4.0/).
Keyphrases
- replacement therapy
- rheumatoid arthritis
- disease activity
- ulcerative colitis
- end stage renal disease
- newly diagnosed
- ejection fraction
- chronic kidney disease
- chronic obstructive pulmonary disease
- prognostic factors
- peritoneal dialysis
- lung function
- minimally invasive
- cystic fibrosis
- combination therapy
- air pollution